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SR-4835

Glpbio
Catalog No：GC39175-25mg CAS No.：2387704-62-1 MDLNo： Brand:Glpbio purity： 特性： Purpose:SR-4835 是有效，高選擇性和 ATP 競(jìng)爭(zhēng)性的 CDK12/CDK13 雙重抑制劑 (CDK12:IC50=99 nM，Kd=98 nM；CDK13:Kd=4.9 nM)。SR-4835 與破壞 DNA 的化學(xué)療法和 PARP 抑制劑協(xié)同作用，并引起三陰性乳腺癌 (TNBC) 細(xì)胞凋亡。DMSO: 5 mg/mL (10.01 mM; ultrasonic and warming and heat to 60°C)
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