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Home > Category > > Small Molecule Compound > BRD3308

BRD3308

Glpbio

Catalog No：GC39551-25mg CAS No.：1550053-02-5 MDLNo： Brand:Glpbio purity： 特性： Purpose:BRD3308 是一種高選擇性的 HDAC3 抑制劑，IC50 為 54 nM。BRD3308 對 HDAC3 的選擇性是 HDAC1 (IC50 為 1.26 μM) 或 HDAC2 (IC50 為 1.34 μM) 的 23 倍。BRD3308 抑制由炎性細胞因子或糖脂毒性應(yīng)激誘導(dǎo)的胰腺 β 細胞凋亡 (apoptosis)，并增加功能性胰島素釋放。BRD3308 還可激活 HIV-1 轉(zhuǎn)錄并破壞 HIV-1 潛伏期。DMSO: 250 mg/mL (870.20 mM)

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Product Overview

Product Name	BRD3308
CAS	1550053-02-5
Formula	C₁₅H₁₄FN₃O₂
MW	287.29
Storage condition	Store at -20°C

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BRD3308

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